3-Hydroxy agomelatine D3

Names

[ CAS No. ]:
1079774-23-4

[ Name ]:
3-Hydroxy agomelatine D3

Biological Activity

[Description]:

3-Hydroxy agomelatine D3 is a deuterium labeled 3-Hydroxy agomelatine. 3-Hydroxy agomelatine is a 5-HT2C receptor antagonist with an IC50 of 3.2 μM and a Ki of 1.8 μM[1].

[Related Catalog]:

Research Areas >> Neurological Disease
Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor
Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor

[Target]

5-HT2C Receptor:3.2 μM (IC50)

5-HT2C Receptor:1.8 μM (Ki)


[References]

[1]. Chagraoui A, et al. Agomelatine(S 20098) antagonizes the penile erections induced by the stimulation of 5-HT2C receptors in Wistar rats. Psychopharmacology (Berl). 2003 Oct;170(1):17-22.

Chemical & Physical Properties

[ Molecular Formula ]:
C15H14D3NO3

[ Molecular Weight ]:
262.32

Related Compounds