SARS-CoV-2 3CLpro-IN-7

Names

[ CAS No. ]:
1164478-67-4

[ Name ]:
SARS-CoV-2 3CLpro-IN-7

Biological Activity

[Description]:

SARS-CoV-2 3CLpro-IN-7 is a reversible covalent SARS-CoV-2 3CL protease inhibitor with an IC50 value of 1.4 µM[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> SARS-CoV

[In Vitro]

SARS-CoV-2 3CLpro-IN-7 (0-100 µM; 5, 30, 60, 180 min) 以剂量和时间依赖性方式抑制 SARS-CoV-2 3CLpro 活性 [1]。

[References]

[1]. Wang L, et al. Discovery of novel SARS-CoV-2 3CL protease covalent inhibitors using deep learning-based screen. Eur J Med Chem. 2022 Dec 15;244:114803.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₄H₁₇ClN₂O₆

[ Molecular Weight ]:
464.85

Related Compounds