β2AR/M3-receptor agonist-1

Names

[ CAS No. ]:
1206887-00-4

[ Name ]:
β2AR/M3-receptor agonist-1

Biological Activity

[Description]:

β2AR/M3-receptor agonist-1 (example 9) is a potent β2AR and M3 receptor agonist. β2AR/M3-receptor agonist-1 shows M3 receptor affinity with a pIC50 value of 9.3. β2AR/M3-receptor agonist-1 has the potential for the research of respiratory tract disorders[1].

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> mAChR
Signaling Pathways >> GPCR/G Protein >> mAChR
Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor
Research Areas >> Metabolic Disease

[Target]

β2 adrenoceptor:>9.2 (pEC50)

M3:9.3 (pIC50)


[References]

[1]. Jonathan Mark Sutton, et al. Nitrogen containing heterocyclic compounds useful as bifunctional modulators of m3 receptors and beta-2 receptors. WO2010015792A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C38H40N4O7.xCH2O2

Related Compounds