Rebamipide D4

Names

[ CAS No. ]:
1219409-06-9

[ Name ]:
Rebamipide D4

Biological Activity

[Description]:

Rebamipide D4 (OPC12759 D4) is deuterium labeled Rebamipide. Rebamipide is a mucoprotective agent. Rebamipide induces COX-2 expression, increases PGE2 levels, and enhances gastric mucosal defense in a COX-2-dependent manner[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor
Research Areas >> Inflammation/Immunology
Signaling Pathways >> Immunology/Inflammation >> COX

[References]

[1]. Sun WH, et al. Induction of cyclooxygenase-2 in rat gastric mucosa by rebamipide, a mucoprotective agent. J Pharmacol Exp Ther. 2000 Nov;295(2):447-52.

Chemical & Physical Properties

[ Melting Point ]:
290-294°C (dec.)

[ Molecular Formula ]:
C19H11D4ClN2O4

[ Molecular Weight ]:
370.7864

[ Storage condition ]:
-20?C Freezer

Related Compounds