hCAII-IN-1

Names

[ CAS No. ]:
1807520-24-6

[ Name ]:
hCAII-IN-1

Biological Activity

[Description]:

hCAII-IN-1 (compound 7f) is a potent and selective inhibitor of carbonic anhydrase (CA II/IX) with Kis of 1.2 and 113.6 nM, respectively. hCAII-IN-1 has the potential for the research of cancer diseases[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Metabolic Enzyme/Protease >> Carbonic Anhydrase

[References]

[1]. Nocentini A, et al. Sulfonamide/sulfamate switch with a series of piperazinylureido derivatives: Synthesis, kinetic and in silico evaluation as carbonic anhydrase isoforms I, II, IV, and IX inhibitors. Eur J Med Chem. 2020;186:111896.

Chemical & Physical Properties

[ Molecular Formula ]:
C21H21BrN6O4S

[ Molecular Weight ]:
533.40

Related Compounds