Acetyl-ACTH (7-24) (human, bovine, rat)

Names

[ CAS No. ]:
1815618-01-9

[ Name ]:
Acetyl-ACTH (7-24) (human, bovine, rat)

[Synonym ]:
L-Proline, 1-[(2R,8S,11S,14S)-11-[3-[(aminoiminomethyl)amino]propyl]-2-(5-aminopentyl)-8-(1H-indol-3-ylmethyl)-1,4,7,10,13,16-hexaoxo-14-(phenylmethyl)-3,6,9,12,15-pentaazaheptadec-1-yl]-L-prolyl-L-valylglycyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-prolyl-L-valyl-D-lysyl-L-valyl-L-tyrosyl-
1-{(2R)-2-[(N-Acetyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl)amino]-7-aminoheptanoyl}-L-prolyl-L-valylglycyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-prolyl-L-valyl-D-lysyl-L-valyl-L-tyrosyl-L-proline

Biological Activity

[Description]:

Acetyl-ACTH (7-24) (human, bovine, rat) causes a marked decrease of ACTH-evoked corticosterone and aldosterone release[1].

[Related Catalog]:

Research Areas >> Metabolic Disease
Research Areas >> Neurological Disease
Signaling Pathways >> Others >> Androgen Receptor

[References]

[1]. M Feuilloley, et al. Structure-activity relationships of monomeric and dimeric synthetic ACTH fragments in perifused frog adrenal slices. J Steroid Biochem. 1990 Apr;35(5):583-92.  

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C107H170N32O21

[ Molecular Weight ]:
2240.70

[ Exact Mass ]:
2253.337402

[ LogP ]:
-0.74

[ Index of Refraction ]:
1.665

Related Compounds