CB2R agonist 1
Names
[ CAS No. ]:
1817633-49-0
[ Name ]:
CB2R agonist 1
Biological Activity
[Description]:
CB2R agonist 1 is a selective ligand of cannabinoid receptor subtype 2 (CB2R) with an EC50 value of 0.56 µM. CB2R agonist 1 has high affinity and excellent selectivity for human CB2R and CB1R respectively. CB2R agonist 1 regulates the production of pro-inflammatory cytokines and anti-inflammatory cytokines and play an immunomodulatory role[1].
[Related Catalog]:
[Target]
CB2R:0.56 μM (EC50)
[In Vitro]
CB2R agonist 1 (Compound 4) (1 和 10 μM;24 h) 以浓度依赖性方式增加单核细胞和巨噬细胞中 IL-4、IL-10 抗炎细胞因子的产生,减少 TNF-α、IFN-γ、IL-1β、IL-6 的产生[1]。
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C22H32N2O
[ Molecular Weight ]:
340.50