MAO-B-IN-14

Names

[ CAS No. ]:
1904610-48-5

[ Name ]:
MAO-B-IN-14

Biological Activity

[Description]:

MAO-B-IN-14 (Compound 9) is a potent and selective monoamine oxidase-B (MAO-B) inhibitor with an IC50 of 0.95 μM and a Ki of 0.55 μM against human MAO-B.

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase
Research Areas >> Neurological Disease

[Target]

hMAO-B:0.95 μM (IC50)

hMAO-B:0.55 μM (Ki)


[References]

[1]. Hammuda A, et al. Design and synthesis of novel chalcones as potent selective monoamine oxidase-B inhibitors. Eur J Med Chem. 2016 May 23;114:162-9.

Chemical & Physical Properties

[ Molecular Formula ]:
C17H14O3S

[ Molecular Weight ]:
298.36

Related Compounds