Boc-Gln-Ala-Arg-pNA hydrochloride salt

Names

[ CAS No. ]:
1926163-47-4

[ Name ]:
Boc-Gln-Ala-Arg-pNA hydrochloride salt

[Synonym ]:
N2-{[(2-Methyl-2-propanyl)oxy]carbonyl}-L-glutaminyl-L-alanyl-N-(4-nitrophenyl)-L-argininamide hydrochloride (1:1)
L-Argininamide, N2-[(1,1-dimethylethoxy)carbonyl]-L-glutaminyl-L-alanyl-N-(4-nitrophenyl)-, hydrochloride (1:1)

Biological Activity

[Description]:

Boc-QAR-pNA is a chromogenic substrate of trypsin. Boc-QAR-pNA can be used to test trypsin activity[1][2].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Ser/Thr Protease
Research Areas >> Cancer

[References]

[1]. Fabritz S, et, al. From pico to nano: biofunctionalization of cube-octameric silsesquioxanes by peptides and miniproteins. Org Biomol Chem. 2012 Aug 21;10(31):6287-93.  

[2]. Avrutina O, et, al. Between two worlds: a comparative study on in vitro and in silico inhibition of trypsin and matriptase by redox-stable SFTI-1 variants at near physiological pH. Org Biomol Chem. 2012 Oct 14;10(38):7753-62.  

Chemical & Physical Properties

[ Molecular Formula ]:
C25H39N9O8

[ Molecular Weight ]:
593.63

[ Exact Mass ]:
629.268860

Related Compounds