N-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-L-Leucine-1-13C

Names

[ CAS No. ]:
202114-53-2

[ Name ]:
N-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-L-Leucine-1-13C

[Synonym ]:
L-Leucine-1-13C,N-Fmoc
N-(9-Fluorenylmethoxycarbonyl)-L-leucine-1-13C,L-Leucine-1-13C,N-Fmoc
MFCD00190328
Fmoc-D-Leu-OH
Leucine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
Fmoc-Leu-OH-1-13C
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]leucine

Biological Activity

[Description]:

Fmoc-leucine-13C is a 13C-labeled Boc-Glycine[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
559.8±33.0 °C at 760 mmHg

[ Melting Point ]:
152-156ºC(lit.)

[ Molecular Formula ]:
C₂₀₁₃CH₂₃NO₄

[ Molecular Weight ]:
354.40

[ Flash Point ]:
292.4±25.4 °C

[ Exact Mass ]:
353.162720

[ PSA ]:
75.63000

[ LogP ]:
4.95

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.583

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3