Propanoic-d5 sodium

Names

[ CAS No. ]:
202529-18-8

[ Name ]:
Propanoic-d5 sodium

[Synonym ]:
Sodium propionate-d5
Propionic-d5 acid sodium salt

Biological Activity

[Description]:

Propanoic-d5 (sodium) is the deuterium labeled Sodium Propionate[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Chemical & Physical Properties

[ Melting Point ]:
285-286ºC(lit.)

[ Molecular Formula ]:
C₃D₅NaO₂

[ Molecular Weight ]:
101.09100

[ Exact Mass ]:
101.05000

[ PSA ]:
40.13000

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H312

[ Precautionary Statements ]:
P280

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
21

[ Safety Phrases ]:
36/37

[ RIDADR ]:
NONH for all modes of transport

Articles

Microorganisms linked to inflammatory bowel disease-associated dysbiosis differentially impact host physiology in gnotobiotic mice.

ISME J. , doi:10.1038/ismej.2015.127, (2015)

Studying host-microbiota interactions are fundamental to understanding the mechanisms involved in intestinal homeostasis and inflammation. In this work, we analyzed these interactions in mice that wer...