SARS-CoV-2 nsp3-IN-2

Names

[ CAS No. ]:
2038858-11-4

[ Name ]:
SARS-CoV-2 nsp3-IN-2

Biological Activity

[Description]:

SARS-CoV-2 nsp3-IN-2 is a macrodomain (Mac1) inhibitor with IC50 value of 180 μM. SARS-CoV-2 nsp3-IN-2 is a small molecule chemical probe and can be used for the research of viral[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Others >> Others

[Target]

IC50: 180 μM (Mac1)[1]


[In Vitro]

SARS-CoV-2 nsp3-IN-2 emonstrates weak potency against Mac1 in an ADP-ribose binding AlphaScreen assay with IC50 value of 180 μM[1].

[References]

[1]. Lavinia M Sherrill, et al. Design, Synthesis and Evaluation of Inhibitors of the SARS-CoV2 nsp3 Macrodomain. bioRxiv. 2022 Feb 28;2022.02.27.482176.

Chemical & Physical Properties

[ Molecular Formula ]:
C10H12N4O2

[ Molecular Weight ]:
220.23

Related Compounds