AChE/hCA I/II-IN-1

Names

[ CAS No. ]:
2049681-10-7

[ Name ]:
AChE/hCA I/II-IN-1

Biological Activity

[Description]:

AChE/hCA I/II-IN-1 (Compound 6) is a potent inhibitor of AChE/Hca with IC50 values of 22.21, 60.79 and 66.64 nM for AChE, Hca Ⅰ and Hca Ⅱ. AChE/hCA I/II-IN-1 can be used for the rsearch for glaucoma, Alzheimer's disease, diabetes[1].

[Related Catalog]:

Research Areas >> Endocrinology
Signaling Pathways >> Metabolic Enzyme/Protease >> Carbonic Anhydrase
Research Areas >> Neurological Disease
Signaling Pathways >> Neuronal Signaling >> AChE

[References]

[1]. Gülçin İ, et al. Synthesis of nitrogen, phosphorus, selenium and sulfur-containing heterocyclic compounds - Determination of their carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase and α-glycosidase inhibition properties. Bioorg Chem. 2020 Oct;103:104171.

Chemical & Physical Properties

[ Molecular Formula ]:
C15H13N3S

[ Molecular Weight ]:
267.35

Related Compounds