HCV-IN-39

Names

[ CAS No. ]:
2087916-31-0

[ Name ]:
HCV-IN-39

Biological Activity

[Description]:

HCV-IN-39 (Compound 18a) is a potent hepatitis C virus (HCV) nucleoside inhibitor with EC50 values of 0.644, 0.952 and 0.154 μM against GT1a, GT1b and GT1b CES1 replicons[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> HCV
Research Areas >> Infection

[Target]

EC50: 0.644 μM (GT1a), 0.952 μM (GT1b), 0.154 μM (GT1b CES1)[1]


[References]

[1]. Chris Krueger A, et al. Synthesis and evaluation of 2'-dihalo ribonucleotide prodrugs with activity against hepatitis C virus. Bioorg Med Chem. 2020 Jan 1;28(1):115208.

Chemical & Physical Properties

[ Molecular Formula ]:
C21H26BrClN3O9P

[ Molecular Weight ]:
610.78

Related Compounds