Sulfo-SPDB linker

Names

[ CAS No. ]:
2095682-79-2

[ Name ]:
Sulfo-SPDB linker

Biological Activity

[Description]:

Sulfo-SPDB linker is a disulfide-cleavable linker used for the antibody-drug conjugate (ADC)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

Research Areas >> Inflammation/Immunology

[Target]

Alkyl/ether

[References]

[1]. Sun X, et al. Effects of Drug-Antibody Ratio on Pharmacokinetics, Biodistribution, Efficacy, and Tolerability of Antibody-Maytansinoid Conjugates. Bioconjug Chem. 2017 May 17;28(5):1371-1381.

Chemical & Physical Properties

[ Molecular Formula ]:
C₄₂H₆₁ClN₄O₁₄S₃

[ Molecular Weight ]:
977.60

Related Compounds