PD-1/PD-L1-IN-19

Names

[ CAS No. ]:
2156651-18-0

[ Name ]:
PD-1/PD-L1-IN-19

Biological Activity

[Description]:

PD-1/PD-L1-IN-19 (Example 22) is a small-molecule inhibitor of the PD-1/PD-L1 protein-protein interaction. PD-1/PD-L1-IN-19 blocks PD-1/PD-L1 with the IC50 of 62.3 nM. PD-1/PD-L1-IN-19 can be used for the research of cancers, infectious diseases and autoimmune diseases[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Immunology/Inflammation >> PD-1/PD-L1

[References]

[1]. Benzyl phenyl ether derivative, preparation method therefor, and pharmaceutical composition and uses thereof. WO2017202273A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C32H29BrClN3O3

[ Molecular Weight ]:
618.95

Related Compounds