PD-1/PD-L1-IN-22

Names

[ CAS No. ]:
2159063-12-2

[ Name ]:
PD-1/PD-L1-IN-22

Biological Activity

[Description]:

PD-1/PD-L1-IN-22 (Example 2) is a small-molecule inhibitor of the PD-1/PD-L1 protein-protein interaction. PD-1/PD-L1-IN-22 blocks PD-1/PD-L1 with the IC50 of 0.732 μM. PD-1/PD-L1-IN-22 can be used for the research of cancers, infectious diseases and autoimmune diseases[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Immunology/Inflammation >> PD-1/PD-L1

[References]

[1]. Phenylate derivative, preparation method therefor, and pharmaceutical composition and uses thereof. WO2017202276A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C25H26BrClN2O3

[ Molecular Weight ]:
517.84

Related Compounds