MAC glucuronide linker

Names

[ CAS No. ]:
2260960-07-2

[ Name ]:
MAC glucuronide linker

Biological Activity

[Description]:

MAC glucuronide linker is a linker for antibody-drug-conjugations (ADCs) and is useful to prepare the MAC glucuronide SN-38 drug linker[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Alkyl/ether

[References]

[1]. Lau UY, et al. Lactone Stabilization is Not a Necessary Feature for Antibody Conjugates of Camptothecins. Mol Pharm. 2018 Sep 4;15(9):4063-4072.

Chemical & Physical Properties

[ Molecular Formula ]:
C₄₃H₄₈BrN₃O₁₇S

[ Molecular Weight ]:
990.82

Related Compounds