MAT2A-IN-3

Names

[ CAS No. ]:
2377493-28-0

[ Name ]:
MAT2A-IN-3

Biological Activity

[Description]:

MAT2A-IN-3 is a potent inhibitor of MAT2A. The expression level of MAT2A is abnormally high in several types of tumors, including gastric, colon, liver and pancreatic cancers. MAT2A-IN-3 reduces the proliferative activity of MTAP-deficient cancer cells. MAT2A-IN-3 has the potential for the research of cancer diseases (extracted from patent WO2019191470A1, compound 265)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> GPCR/G Protein >> Somatostatin Receptor

[References]

[1]. Zenon D. Konteatis, et al. Heterobicyclic inhibitors of mat2a and methods of use for treating cancer. Patent WO2019191470A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C24H16F5N5O3

[ Molecular Weight ]:
517.41


Related Compounds