E3 ligase Ligand 22

Names

[ CAS No. ]:
2377849-57-3

[ Name ]:
E3 ligase Ligand 22

Biological Activity

[Description]:

E3 ligase Ligand 22 (compound 139) is a cereblon binder for the degradation of Ikaros or Aiolos by the ubiquitin proteasome pathway[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> Ligand for E3 Ligase

[Target]

Cereblon


[References]

[1]. Gesine Kerstin VEITS, et al. Cereblon binders for the degradation of ikaros. WO2019191112A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C28H34N6O4

[ Molecular Weight ]:
518.61

Related Compounds