TRβ agonist 3

Names

[ CAS No. ]:
2411099-46-0

[ Name ]:
TRβ agonist 3

Biological Activity

[Description]:

TRβ agonist 3 (Compound 3) is a potent agonist of TRβ. TRβ agonist 3 reduces lipid accumulation in HepG2 and promote lipolysis with comparable effects. TRβ agonist 3 is a new potential TRβ-selective thyromimetics[1].

[Related Catalog]:

Signaling Pathways >> Others >> Thyroid Hormone Receptor
Research Areas >> Metabolic Disease

[References]

[1]. Runfola M, et al. Design, synthesis and biological evaluation of novel TRβ selective agonists sustained by ADME-toxicity analysis. Eur J Med Chem. 2020 Feb 15;188:112006.

Chemical & Physical Properties

[ Molecular Formula ]:
C20H25NO3

[ Molecular Weight ]:
327.42

Related Compounds