PIN1 inhibitor 2

Names

[ CAS No. ]:
2417101-28-9

[ Name ]:
PIN1 inhibitor 2

Biological Activity

[Description]:

PIN1 inhibitor 2 (compound 12) is a potent PIN1 inhibitor. PIN1 inhibitor 2 shows antitumor activity with an IC50 of 9.55 µM for MCF7 cells. PIN1 inhibitor 2 has the potential for the research of breast cancer[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Epigenetics >> MicroRNA

[Target]

PIN1[1]


[References]

[1]. Nashaat S,et al. Synthesis, state-of-the-art NMR-binding and molecular modeling study of new benzimidazole core derivatives as Pin1 inhibitors: Targeting breast cancer. Bioorg Med Chem. 2020 Jun 1;28(11):115495.

Chemical & Physical Properties

[ Molecular Formula ]:
C16H21N3S2

[ Molecular Weight ]:
319.49

Related Compounds