Aldose reductase-IN-4

Names

[ CAS No. ]:
2446136-17-8

[ Name ]:
Aldose reductase-IN-4

Biological Activity

[Description]:

Aldose reductase-IN-4 (compund IIc) is an aldose reductase inhibitor with IC50s of 11.70 μM and 0.98 μM for aldehyde reductase 1 (ALR1) and ALR2, respectively[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Metabolic Enzyme/Protease >> Aldose Reductase

[Target]

IC50: 11.70 μM (Aldehyde reductase 1) and 0.98 μM (Aldehyde reductase 2)[1]


[References]

[1]. Konstantinos Koutsopoulos, et al. Design synthesis and evaluation of novel aldose reductase inhibitors: The case of indolyl-sulfonyl-phenols. Bioorg Med Chem. 2020 Aug 1;28(15):115575.

Chemical & Physical Properties

[ Molecular Formula ]:
C14H10FNO3S

[ Molecular Weight ]:
291.30

Related Compounds