AKT-IN-13
Names
[ CAS No. ]:
2459489-51-9
[ Name ]:
AKT-IN-13
Biological Activity
[Description]:
AKT-IN-13 (compound 4b) is a potent Akt inhibitor with IC50s of 1.6 nM, 2.4 nM and 0.3 nM for Akt1, Akt2 and Akt3, respectively. AKT-IN-13 can be used for researching anticancer[1].
[Related Catalog]:
[Target]
Akt1:1.6 nM (IC50)
Akt2:2.4 nM (IC50)
Akt3:0.3 nM (IC50)
[In Vitro]
AKT-IN-13 (compound 4b) displays good potency in the LNCap cell line with an IC50 value of 103 nM and a high free fraction with 51.3% human plasma protein binding (PPB)[1].
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C24H31ClN6O2
[ Molecular Weight ]:
470.99