IL-17A modulator-3

Names

[ CAS No. ]:
2467732-95-0

[ Name ]:
IL-17A modulator-3

Biological Activity

[Description]:

IL-17A modulator-3 (compound 253) is a IL-17A modulator. IL-17A modulator-3 inhibits IL-17A/A with an IC50 value ＜10 μM. IL-17A modulator-3 can be used for the research of inflammation, cancer and autoimmune disease[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Immunology/Inflammation >> Interleukin Related
Research Areas >> Inflammation/Immunology

[Target]

IC50: ＜10 μM (IL-17A/A)[1]


[In Vitro]

IL-17A modulator-3 (0-10 μM; 20 h) inhibits IL-17A/A with an IC50 value ＜10 μM in HEK-Blue IL-17A reporter cell line[1].

[References]

[1]. Fatheree, Paul R, et al. Amidoamide ligands as IL-17 modulators and their preparation. US20200247785. 2020.

Chemical & Physical Properties

[ Molecular Formula ]:
C34H50FN7O4

[ Molecular Weight ]:
639.80

Related Compounds