HCV-IN-41

Names

[ CAS No. ]:
2468169-71-1

[ Name ]:
HCV-IN-41

Biological Activity

[Description]:

HCV-IN-41 (compound 4) is a highly potent hepatitis C virus (HCV) inhibitor with an EC50 value of 0.006762 nM, 5.183 nM, 1.365 nM and 142.2 nM for HCV genotype 1b, 2a, 3a and 4a, respectively. HCV-IN-41 reduces HCV RNA replication[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> HCV
Research Areas >> Infection

[Target]

IC50: 0.006762 nM (HCV 1b), 5.183 nM (HCV 2a), 1.365 nM (HCV 3a), 142.2 nM (HCV 4a)[1]


[References]

[1]. Abdel Karim SE, et al. Symmetric benzidine derivatives as anti-HCV agents: Insight into the nature, stereochemistry of the capping amino acid and the size of the terminal capping carbamates. Bioorg Chem. 2020 Sep;102:104089.

Chemical & Physical Properties

[ Molecular Formula ]:
C48H56N6O8

[ Molecular Weight ]:
844.99

Related Compounds