KRAS G12C inhibitor 55

Names

[ CAS No. ]:
2508134-76-5

[ Name ]:
KRAS G12C inhibitor 55

Biological Activity

[Description]:

KRAS G12C inhibitor 55 (Compound 1) is a KRAS G12C inhibitor[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> GPCR/G Protein >> Ras

[Target]

KRAS(G12C)


[In Vitro]

KRAS G12C inhibitor 55 (Compound 1) shows inhibition for CALU-1 cells with an IC50 of 2.7 nM[1].

[References]

[1]. Hao Wu, et al. Quinazoline compound and pharmaceutical composition thereof. WO2022083616A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C36H40F3N7O2

[ Molecular Weight ]:
659.74

Related Compounds