hMAO-B-IN-3

Names

[ CAS No. ]:
2581113-51-9

[ Name ]:
hMAO-B-IN-3

Biological Activity

[Description]:

hMAO-B-IN-3 (Compound 15) is a potent inhibitor of hMAO-B with an IC50 of 47.4 nM. hMAO-B-IN-3 is playing favourable drug-like properties and a broad safety window. hMAO-B-IN-3 is thus a suitable candidate for lead optimization and the development of multitarget-directed ligands[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Neurological Disease

[References]

[1]. Chavarria D, et al. Design of novel monoamine oxidase-B inhibitors based on piperine scaffold: Structure-activity-toxicity, drug-likeness and efflux transport studies. Eur J Med Chem. 2020 Jan 1;185:111770.

Chemical & Physical Properties

[ Molecular Formula ]:
C20H15NO4

[ Molecular Weight ]:
333.34

Related Compounds