MIF-IN-5

Names

[ CAS No. ]:
2582755-31-3

[ Name ]:
MIF-IN-5

Biological Activity

[Description]:

MIF-IN-5 (compound 1d) is a potent and reversible macrophage migration inhibitory factor (MIF) competitive inhibitor with an IC50 of 4.8 μM and a Ki value of 3.3 μM, respectively[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology
Research Areas >> Metabolic Disease

[Target]

IC50: 4.8 μM (MIF)[1] Ki: 3.3 μM (MIF)[1]


[References]

[1]. Xiao Z, Fokkens M, Chen D, et al. Structure-activity relationships for binding of 4-substituted triazole-phenols to macrophage migration inhibitory factor (MIF). Eur J Med Chem. 2020;186:111849.

Chemical & Physical Properties

[ Molecular Formula ]:
C18H14FN5O2

[ Molecular Weight ]:
351.33

Related Compounds