Fulvestrant 3-β-D-Glucuronide

Names

[ CAS No. ]:
261506-27-8

[ Name ]:
Fulvestrant 3-β-D-Glucuronide

[Synonym ]:
(7α,17β)-17-Hydroxy-7-{9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl}estra-1,3,5(10)-trien-3-yl β-D-glucopyranosiduronic acid
β-D-Glucopyranosiduronic acid, (7α,17β)-17-hydroxy-7-[9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl]estra-1,3,5(10)-trien-3-yl

Biological Activity

[Description]:

Fulvestrant 3-β-D-Glucuronide, a metabolite, is glucuronide and sulfate conjugates of Fulvestrant (HY-13636), a pure anti-estrogenic steroid. Fulvestrant 3-β-D-Glucuronide can be used for the research of breast cancer[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. John R Ferguson, et al. Glucuronide and sulfate conjugates of ICI 182,780, a pure anti-estrogenic steroid. Order of addition, catalysis and substitution effects in glucuronidation.2000, 41(3), 389–392.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
863.2±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C38H55F5O9S

[ Molecular Weight ]:
782.895

[ Flash Point ]:
475.8±34.3 °C

[ Exact Mass ]:
782.348694

[ LogP ]:
5.61

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.552

Related Compounds