SOS1-IN-12

Names

[ CAS No. ]:
2654741-56-5

[ Name ]:
SOS1-IN-12

Biological Activity

[Description]:

SOS1-IN-12 is a potent son of sevenless homolog 1 (SOS1) inhibitor with a Ki of 0.11 nM for SOS1 and an IC50 of 47 nM for pERK. SOS1-IN-13 can be used for researching anticancer[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> GPCR/G Protein >> Ras

[Target]

Ki: 0.11 nM (SOS1)[1] IC50: 47 nM (pERK)[1]


[References]

[1]. Matthew Arnold Marx, et al. Sos1 inhibitors. WO2021127429A1 (compound 6-4)

Chemical & Physical Properties

[ Molecular Formula ]:
C23H26F3N5

[ Molecular Weight ]:
429.48

Related Compounds