Methoprene-d7

Names

[ CAS No. ]:
2673270-24-9

[ Name ]:
Methoprene-d7

Biological Activity

[Description]:

Methoprene-d7 is the deuterium labeled Methoprene[1]. Methoprene, an insect juvenile growth hormone mimic, is a growth-regulating insecticide that manifests its toxicity to target organisms by acting as a juvenile hormone agonist[2][3].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Olmstead AW, LeBlanc GL. Low exposure concentration effects of methoprene on endocrine-regulated processes in the crustacean Daphnia magna. Toxicol Sci. 2001;62(2):268-273.  

[3]. Monteiro JP, et al. Toxicity of methoprene as assessed by the use of a model microorganism. Toxicol In Vitro. 200519(7):951-956.  

Chemical & Physical Properties

[ Molecular Formula ]:
C19H27D7O3

[ Molecular Weight ]:
317.51

Related Compounds