IDO1-IN-17

Names

[ CAS No. ]:
2677054-58-7

[ Name ]:
IDO1-IN-17

Biological Activity

[Description]:

IDO1-IN-17 (I-4) is an IDO1 inhibitor, with an IC50 of 0.44 μM in hela cells[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Metabolic Enzyme/Protease >> Indoleamine 2,3-Dioxygenase (IDO)

[Target]

IDO1:0.44 μM (IC50, in hela cells)

[References]

[1]. Yunze Wu, et al. Discovery of novel IDO1 inhibitors targeting the protein's apo form through scaffold hopping from holo-IDO1 inhibitor. Bioorg Med Chem Lett. 2021 Nov 15;52:128373.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₈H₃₂BrClFN₅O₂

[ Molecular Weight ]:
604.94

Related Compounds