Fluorescent polyamine probe-1

Names

[ CAS No. ]:
2678634-03-0

[ Name ]:
Fluorescent polyamine probe-1

Biological Activity

[Description]:

Fluorescent polyamine probe-1 (compound 15) is a linear polyamine probe with high uptake efficiency. Fluorescent polyamine probe-1 can be used for the research of transport system into cancer cells[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

Fluorescent polyamine probe-1 在癌细胞 MCF-7 中迅速积累，但在非致瘤细胞 MCF-10A 中不积累[1]。 Fluorescent polyamine probe-1 (4 h) 在 MCF-7 中的摄取效率比支链探针高 10 倍，并且在探针加入后的一小时就可以观察探针在细胞内积累[1]。

[References]

[1]. Vanhoutte R, et al. Clickable Polyamine Derivatives as Chemical Probes for the Polyamine Transport System. Chembiochem. 2018 May 4;19(9):907-911.  

Chemical & Physical Properties

[ Molecular Formula ]:
C28H45BF2N8

[ Molecular Weight ]:
542.52

Related Compounds