N-Desmethyl dosimertinib-d5
Names
[ CAS No. ]:
2719691-00-4
[ Name ]:
N-Desmethyl dosimertinib-d5
Biological Activity
[Description]:
N-Desmethyl dosimertinib-d5 is the deuterium labeled Dosimertinib (HY-142283). Dosimertinib is a highly potent, selective, and orally active deuterated EGFR inhibiotor. Dosimertinib can be used for the research of non-small-cell lung cancer[1][2].
[Related Catalog]:
[In Vitro]
氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C27H26D5N7O2
[ Molecular Weight ]:
490.61