BODIPY FL thalidomide

Names

[ CAS No. ]:
2740620-18-0

[ Name ]:
BODIPY FL thalidomide

Biological Activity

[Description]:

BODIPY FL thalidomide is a high-affinity fluorescent probe for the human cereblon protein with a Kd value of 3.6 nM[1]

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> PROTAC >> Ligand for E3 Ligase

[References]

[1]. Lin W, et al. Development of BODIPY FL Thalidomide As a High-Affinity Fluorescent Probe for Cereblon in a Time-Resolved Fluorescence Resonance Energy Transfer Assay. Bioconjug Chem. 2020 Nov 18;31(11):2564-2575.  

Chemical & Physical Properties

[ Molecular Formula ]:
C37H43BF2N6O7

[ Molecular Weight ]:
732.58

Related Compounds