AChE-IN-19

Names

[ CAS No. ]:
2742707-36-2

[ Name ]:
AChE-IN-19

Biological Activity

[Description]:

AChE-IN-19 (compound A15) is a highly potent AChE inhibitor with an IC50 value of 0.56 μM, also inhibits Aβ aggregation. AChE-IN-19 has potent neuroprotective activities and nearly no toxicity on SH-SY5Y cells. AChE-IN-19 can be used for researching Alzheimer's disease[1].

[Related Catalog]:

Research Areas >> Neurological Disease
Signaling Pathways >> Neuronal Signaling >> AChE

[Target]

IC50: 0.56 μM (AChE)[1]


[References]

[1]. Shi S, et al. Semi-synthesis and biological evaluation of flavone hybrids as multifunctional agents for the potential treatment of Alzheimer's disease. Bioorg Chem. 2020 Jul;100:103917.

Chemical & Physical Properties

[ Molecular Formula ]:
C30H33NO7

[ Molecular Weight ]:
519.59

Related Compounds