HCV-IN-36

Names

[ CAS No. ]:
2757963-81-6

[ Name ]:
HCV-IN-36

Biological Activity

[Description]:

HCV-IN-36 (compound (S)-3h) is an orally active and potent HCV entry inhibitor. HCV-IN-36 shows excellent antiviral activity, with an EC50 of 0.016 μM and a CC50 (half-maximal cytotoxic concentration) of 8.78 μM[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> HCV
Research Areas >> Infection

[Target]

EC50: 0.016 ± 0.007 μM (HCV)[1]


[References]

[1]. Wang Y, Li J, Tan J, Yang B, Quan Y, Peng Z, Li Y, Li Z. Design, Synthesis, and Biological Evaluation of 2-((4-Bisarylmethyl-piperazin-1-yl)methyl)benzonitrile Derivatives as HCV Entry Inhibitors. J Med Chem. 2022 Feb 10;65(3):2107-2121.

Chemical & Physical Properties

[ Molecular Formula ]:
C30H36ClN5

[ Molecular Weight ]:
502.09

Related Compounds