ALK5-IN-30

Names

[ CAS No. ]:
2785430-86-4

[ Name ]:
ALK5-IN-30

Biological Activity

[Description]:

ALK5-IN-30 (EX-07) is a potent ALK inhibitor, inhibits ALK5 and TGFβ-R1 with both IC50s <10 nM[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ALK

[Target]

IC50: <10 nM (ALK5)[1]

[In Vitro]

ALK5-IN-30 (EX-07) exhibits kinase selectivity on ALK5 over ALK2, with selectivity index of ALK2/ALK5 >10[1].

[References]

[1]. Petermann Oliver, et al. Preparation of carboxymethyl cellulose having improved storage stability: World Intellectual Property Organization, WO2022162133[P]. 2022-08-04.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₄H₂₅FN₈

[ Molecular Weight ]:
444.51

Related Compounds