YCT529 free acid

Names

[ CAS No. ]:
2863670-66-8

[ Name ]:
YCT529 free acid

Biological Activity

[Description]:

YCT529 free acid is a potent, selective and orally active RAR-α inhibitor[1].

[Related Catalog]:

Research Areas >> Endocrinology

Signaling Pathways >> Metabolic Enzyme/Protease >> RAR/RXR

[Target]

RAR-α[1]

[In Vivo]

口服给雄性小鼠 4 周后，YCT529 可显著降低精子数量，预防怀孕的有效性为 99%，且没有任何明显的副作用。在停止接受 YCT529 后 4-6 周，小鼠可以再次生育幼崽[1]。

[References]

[1]. American Chemical Society. 2022.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₉H₂₅NO₃

[ Molecular Weight ]:
435.51

Related Compounds