Methyl (2H31)hexadecanoate

Names

[ CAS No. ]:
29848-79-1

[ Name ]:
Methyl (2H31)hexadecanoate

[Synonym ]:
Hentetracontylalkohol
Methylperdeuteriopalmitat
Perdeuteriertes Methylpalmitat
1-HENTETRACONTANOL
hentriaconta-C-deuterio-hexadecanoic acid methyl ester
Methyl-perdeuterio-hexadecanoat
n-Hentetracontanol-1
Methyl (H)hexadecanoate
hentetracontanol
Hexadecanoic-d acid, methyl ester
hentetracontyl alcohol
Methyl-perdeuteriumhexadecanoat

Biological Activity

[Description]:

Methyl palmitate-d31 is the deuterium labeled Methyl palmitate. Methyl palmitate, an acaricidal compound occurring in green walnut husks, inhibits phagocytic activity and immune response. Methyl palmitate also posseses anti-inflammatory and antifibrotic effects[1][2][3].

[Related Catalog]:

Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. El-Demerdash E, et al, Anti-inflammatory and antifibrotic effects of methyl palmitate. Toxicol Appl Pharmacol. 2011 Aug 1;254(3):238-44.

[3]. N. R. Di Luzio, et al. Depression of phagocytic activity and immune response by methyl palmitate. Am J Physiol. 1964 May;206:939-43.

[4]. Y. N. Wang, et al. Methyl Palmitate, an Acaricidal Compound Occurring in Green Walnut Husks. Journal of Economic Entomology, Volume 102, Issue 1, 1 February 2009, Pages 196–202.

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
332.1±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C17H3D31O2

[ Molecular Weight ]:
301.64

[ Flash Point ]:
152.8±7.5 °C

[ Exact Mass ]:
301.450470

[ PSA ]:
26.30000

[ LogP ]:
7.62

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.441

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds