α-Amylase/α-Glucosidase-IN-1

Names

[ CAS No. ]:
329783-03-1

[ Name ]:
α-Amylase/α-Glucosidase-IN-1

Biological Activity

[Description]:

α-Amylase/α-Glucosidase-IN-1 (compound 33) is a potent α-amylase/α-glucosidase inhibitor with IC50s of 2.01, 2.09 µM for α-amylase and α-glucosidase, respectively. Kinetic studies predict that α-Amylase/α-Glucosidase-IN-1 has the potential of anti hyperglycemia[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Metabolic Disease

[Target]

EC50: 2.01 µM (α-amylase); 2.09 µM (α-glucosidase)[1]


[References]

[1]. Yeye EO,et al. Syntheses, in vitro α-amylase and α-glucosidase dual inhibitory activities of 4-amino-1,2,4-triazole derivatives their molecular docking and kinetic studies. Bioorg Med Chem. 2020 Jun 1;28(11):115467.

Chemical & Physical Properties

[ Molecular Formula ]:
C11H9N5

[ Molecular Weight ]:
211.22

Related Compounds