Antituberculosis agent-3

Names

[ CAS No. ]:
369606-71-3

[ Name ]:
Antituberculosis agent-3

Biological Activity

[Description]:

Antituberculosis agent-3 (Compound 2) is an antituberculosis agent. Antituberculosis agent-3 shows anti-mycobacterial activity, and can inhibit M. tuberculosis H37Rv strain growth (MIC=12.5 μg/mL)[1].

[Related Catalog]:

Research Areas >> Infection
Research Areas >> Inflammation/Immunology
Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

Antituberculosis agent-3 (0-100 μM; 60 min) shows no inhibition of PknB activity[1]. Cell Viability Assay[1] Cell Line: M. tuberculosis Concentration: 0-100 μM Incubation Time: 60 min Result: Displayed no PknB inhibition (IC50>128 μM).

[References]

[1]. Paptawan Thongdee, et al. Virtual Screening Identifies Novel and Potent Inhibitors of Mycobacterium tuberculosis PknB with Antibacterial Activity. J Chem Inf Model. 2022 Aug 22.

Chemical & Physical Properties

[ Molecular Formula ]:
C21H20BrN3O4S

[ Molecular Weight ]:
490.37

Related Compounds