ALDH3A1-IN-2

Names

[ CAS No. ]:
374635-48-0

[ Name ]:
ALDH3A1-IN-2

Biological Activity

[Description]:

ALDH3A1-IN-2 (Compound 19) is a potent inhibitor of ALDH3A1 with an IC50 of 1.29 μM. Aldehyde dehydrogenases (ALDHs) are overexpressed in various tumor types including prostate cancer. ALDH3A1-IN-2 has the potential for the research of cancer diseases[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Aldehyde Dehydrogenase (ALDH)
Research Areas >> Cancer

[References]

[1]. Ibrahim AIM, et al. Expansion of the 4-(Diethylamino)benzaldehyde Scaffold to Explore the Impact on Aldehyde Dehydrogenase Activity and Antiproliferative Activity in Prostate Cancer. J Med Chem. 2022 Mar 10;65(5):3833-3848.

Chemical & Physical Properties

[ Molecular Formula ]:
C11H14N2O3

[ Molecular Weight ]:
222.24


Related Compounds