Antimalarial agent 17

Names

[ CAS No. ]:
508187-76-6

[ Name ]:
Antimalarial agent 17

[Synonym ]:
N-Benzyl-1-[(4-chlorophenyl)sulfonyl]-4-piperidinecarboxamide
4-Piperidinecarboxamide, 1-[(4-chlorophenyl)sulfonyl]-N-(phenylmethyl)-

Biological Activity

[Description]:

Antimalarial agent 17 is an antimalarial agent, also acts as a herbicide. Antimalarial agent 17 is photosystem II inhibitor, shows post-emergence herbicidal activity equal to commercial herbicides[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

Antimalarial agent 17 (compound 7) (25, 50, 100, 200, 400 mg/L; 出苗前使用) 对拟南芥 (A. thaliana.) 表现出较强的芽后除草活性[1]。

[References]

[1]. Corral MG, et al. Exploiting the Evolutionary Relationship between Malarial Parasites and Plants To Develop New Herbicides. Angew Chem Int Ed Engl. 2017 Aug 7;56(33):9881-9885.  

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Molecular Formula ]:
C19H21ClN2O3S

[ Molecular Weight ]:
392.9

[ Exact Mass ]:
392.096130

[ LogP ]:
3.38

[ Index of Refraction ]:
1.610

Related Compounds