SARS-CoV-2 nsp13-IN-2

Names

[ CAS No. ]:
522660-61-3

[ Name ]:
SARS-CoV-2 nsp13-IN-2

Biological Activity

[Description]:

SARS-CoV-2 nsp13-IN-2 (Compound C2) is a SARS-CoV-2 non-structural protein 13 (nsp13) small-molecule inhibitor with an IC50 of 42 μM against nsp13 ssDNA+ ATPase[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> SARS-CoV

[Target]

IC50: 42 μM (nsp13 ssDNA+ ATPase)[1]


[References]

[1]. Yazdi AK, et al. Kinetic Characterization of SARS-CoV-2 nsp13 ATPase Activity and Discovery of Small-Molecule Inhibitors. ACS Infect Dis. 2022 Jul 13.

Chemical & Physical Properties

[ Molecular Formula ]:
C20H18N6OS2

[ Molecular Weight ]:
422.53


Related Compounds