LHRH (1-5) (free acid) trifluoroacetate salt

Names

[ CAS No. ]:
52434-75-0

[ Name ]:
LHRH (1-5) (free acid) trifluoroacetate salt

[Synonym ]:
pglu-his-trp-ser-tyr
pyr-his-trp-ser-tyr-oh

Biological Activity

[Description]:

LHRH (1-5) (free acid) is a polypeptide generated by the cleavage of LHRH at the Tyr55-Gly66 site. LHRH (1-5) (free acid) is converted into LHRH (1-3) and LHRH (4-5) fragments under the catalysis of Angiotensin-converting enzyme (HY-P2983)[1][2].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. McDermott JR, et al. Mechanism of degradation of LH-RH and neurotensin by synaptosomal peptidases. Peptides. 1983 Jan-Feb;4(1):25-30.  

[2]. Yokosawa H, et al. Degradation of luteinizing hormone-releasing hormone by neuroblastoma cells and their membrane: evidence for the involvement of a thiol protease and angiotensin-converting enzyme. J Neurochem. 1987 Jan;48(1):293-8.  

Chemical & Physical Properties

[ Molecular Formula ]:
C34H38N8O9

[ Molecular Weight ]:
702.71

[ Exact Mass ]:
702.27600

[ PSA ]:
267.73000

[ LogP ]:
0.81160

Synthetic Route

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Precursor & DownStream

Precursor

DownStream

Related Compounds