Carbonic anhydrase inhibitor 7

Names

[ CAS No. ]:
546105-61-7

[ Name ]:
Carbonic anhydrase inhibitor 7

Biological Activity

[Description]:

Carbonic anhydrase inhibitor 7 (compound 5b) is a potent inhibitor of human carbonic anhydrase (hCA), with Kis of 6.5 nM, 7.1 nM, 72.1 nM, and 255.8 nM for hCA IX, hCA II, hCA XII and hCA I, respectively[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Metabolic Enzyme/Protease >> Carbonic Anhydrase

[References]

[1]. Swain B, et, al. Exploration of 2-phenylquinoline-4-carboxamide linked benzene sulfonamide derivatives as isoform selective inhibitors of transmembrane human carbonic anhydrases. Eur J Med Chem. 2022 Apr 15;234:114247.

Chemical & Physical Properties

[ Molecular Formula ]:
C23H17N3O5S

[ Molecular Weight ]:
447.46

Related Compounds