Kemptide (amide)

Names

[ CAS No. ]:
70691-36-0

[ Name ]:
Kemptide (amide)

[Synonym ]:
(S)-2-Amino-4-methyl-pentanoic acid {(S)-1-[(S)-1-((S)-1-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-3-methyl-butylcarbamoyl]-2-hydroxy-ethylcarbamoyl}-ethylcarbamoyl)-4-guanidino-butylcarbamoyl]-4-guanidino-butyl}-amide

Biological Activity

[Description]:

Kemptide (amide) is a heptapeptide with properties of a cytophilic substrate. Kemptide is a molecule preserving cell membrane intactness, is phosphorylated by PKI, the inhibitory protein specific for cAMP-dependent protein kinase (PK)[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. Kübler D, et al. Evidence for ecto-protein kinase activity that phosphorylates Kemptide in a cyclic AMP-dependent mode. J Biol Chem. 1989 Aug 25;264(24):14549-55.  

Chemical & Physical Properties

[ Molecular Formula ]:
C32H62N14O8

[ Molecular Weight ]:
770.92400

[ Exact Mass ]:
770.48800

[ PSA ]:
387.74000

[ LogP ]:
1.09800

Related Compounds