CYP1B1-IN-1

Names

[ CAS No. ]:
842122-33-2

[ Name ]:
CYP1B1-IN-1

Biological Activity

[Description]:

CYP1B1-IN-1 (Compound 9e) is a selective cytochrome P450 1B1 (CYP1B1) inhibitor with an IC50 of 0.49 nM[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450

[Target]

IC50: 0.49 nM (CYP1B1), 5.2 nM (CYP1A1), 73.6 nM (CYP1A2)[1]

[References]

[1]. Dong J, et al. Synthesis and structure-activity relationship studies of α-naphthoflavone derivatives as CYP1B1 inhibitors. Eur J Med Chem. 2020 Feb 1;187:111938.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₁₁ClO₂

[ Molecular Weight ]:
306.74

Related Compounds